has a role in the progression of steatosis to steatohepatitis that was
observed in Pemt
mice fed the CD diet for 3 days
An abnormal ratio of PC/PE also can impair other aspects of liver
function. In Pemt
mice, a decreased PC/PE ratio was associated
with lower survival rates after partial hepatectomy
Moreover,
the ratio of PC to PE was inversely correlated with the development of
non-alcoholic fatty liver disease (NAFLD) in mice fed a high fat diet.