Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents to treat cancer. They are coordination complexes of platinum. These drugs are used to treat almost 50% of cancer patients. In this form of chemotherapy, popular drugs include cisplatin and carboplatin, but several have been proposed or are under development.[1]
The main dose-limiting side effect of cancer treatment with platinum compounds is neurotoxicity, which causes peripheral neuropathies including polyneuropathy.[2]