We thus found
that human milk, bovine whey and casein respectively,
affect release of GLP-1, with the human milk resulting
in a significantly higher early response compared to the
WWB meal. In relation to the human milk, the whey meal yielded a higher GLP-1 response. However, considering
the fact that the protein content in the human
milk meal constitutes only about 22% of that in the bovine
whey meal, the early GLP-1 response (iAUC 0–30
min) still reached more than 50% of that seen following
whey. Thus, it could be suggested that human milk is
prone to stimulate GLP-1. It remains to be shown if the
GLP-1 response is solely related to the proteins in the
human milk, or if other bioactive components may also
be involved.