Introduction
Sustainable resources, which are in need of human beings,
are derived from plant biomass. Cellulose is the major
component of plant biomass [1]. Plants produce 4×109
tons of cellulose annually [2]. It is a polymer of β-1,4 linked
glucose units. Its crystalline structure and insoluble
nature represents a big challenge for enzymatic hydrolysis.
Microorganisms are important in conversion of lignocellulose
wastes into valuable products like biofuels produced
by fermentation [3]. Successful bioconversion of cellulosic
materials mainly depends on the nature of cellulose,
sources of cellulolytic enzyme and optimal conditions for
catalytic activity and production of enzymes [4]. Cellulose
quality, temperature, aeration, carbon sources, incubation
period, medium additives, pH of the medium and presence
of inducers are important parameters for the optimized
production of cellulase enzymes [5]. For many years,
cellulose degrading bacteria have been isolated and characterized
for obtaining more effective cellulases from variety
of sources such as soil, decayed plant materials, hot
springs, organic matters, feces of ruminants and composts
[6]. Researchers keep on working to isolate microorganisms
with higher cellulase activity [7]. Present study is
aimed to isolate bacteria, which can produce more efficient
cellulase enzymes in submerged fermentation.