The commercial
release of Serenade Optimum (Bayer Crop Science) in 2013
proved that the interest in B. subtilis as a biocontrol agent is high.
In China, approximately 30 wettable-powder or aqueous formulations
of the bacterium B. subtilis have been licensed and released.
Major constraints for the successful distribution and use of
wettable powders are their short shelf life (usually less than
1 year), the environmental impact of dust pollution, and the strong
odor generated during manufacturing