Abstract—Snail slime (Achatina fulica) has many functions,
including wound or scratch and gingivitis healings, and skin
care. The essential substances contained in the snail slime
involve glycosaminoglycans and proteins. The proteins have
important biological functions, including as a bacterial
protein (enzyme) binding receptor. Chitosan is a natural
polymer containing a hydroxyl group (OH) and amine
groups (NH2) which is positively charged in acidic solution.
It is antimicrobial and polycationic, so that it can be used as
a coagulant agent. The research aims at finding out the
effectiveness of snail slime and chitosan in wound healing.
The methods employed in the research included isolation of
snail slime, the synthesis of chitosan (2%), and in vivo
treatment stages using 5 groups of mice as negative controls,
snail slime and chitosan (2%). The ratios of snail slime and
chitosan examined were 1: 1, 1: 2, and 2: 1. The result shows
that snail slime and chitosan (2%) with the ratio of 1: 2 is
effective in wound healing. The content of the antiinflammatory
factor in snail slime and antimicrobial.