Biological plausibility for a protective effect of magnesium is substantial, but the specificity is
less evident due to the multifactorial aetiology of CVD. In addition to an increased risk of sudden
death, it has been suggested that intake of water low in magnesium may be associated with a
higher risk of motor neuronal disease, pregnancy disorders (so-called preeclampsia), sudden death
in infants, and some types of cancer. Recent studies suggest that the intake of soft water, i.e. water
low in calcium, is associated with a higher risk of fracture in children, certain neurodegenerative
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diseases, pre-term birth and low weight at birth and some types of cancer. Furthermore, the
possible role of water calcium in the development of CVD cannot be excluded.