Degradation is a basic characteristic of polymers and plastics. It is based on the fact that most of these materials are in fact organic compounds that can undergo physical oxidation (thermal and radiative), as well as mechanically- (shear, compression) and chemically- (solvolysis with hydrolysis having major impact) induced degradation. During the early development of polymers and plastics, degradation was generally a process that was to be reduced and eventually avoided in order to guarantee for durability and long service life span of plastics. In the more recent period this view has somehow integrated with the acceptance and promotion of degradation as a desirable positive attribute of certain plastic items and hence relevant parent polymeric materials. This is the case in materials and products that have a limited lifetime during which they should carry out their function and then degrade with eventually bio-promoted mineralization. The degradation process can occur by means of abiotic or biotic events, however, most often a combination of both is at work. Both degradation events can be comprised in the term environmental degradation, so it is common sense to use correspondingly the term: environmentally degradable polymers and plastics (EDPs). Recently, EDPs are finding an increasing number of uses that extend from agriculture and consumer products to medical implants.