Data analysis
Statistical analysis was done using SPSS for windows
version 20.0 (SPSS, Chicago, IL, USA). Since all patients
were hospitalized and we did not have any missing data,
we followed the per protocol strategy for data analysis and
we used Chi-square, independent t-test, Fisher exact test and
Kolmogorov–Smirnov and ANOVA with repeated measures
test. P < 0.05 was considered significant