Though specifically it was observed that, period of collect of the plant followed by plant part (flowers) and method of extraction were important factors in optimization, which can affect variations of yield (Fig. 1). It is evident from the present investigation that R.adpressum flowers are a good source of phenolics as compared to another species belonging to Asteraceae family (Ben Sassi et al., 2008; Falleh et al., 2008). It can also be deduced that April is the best period of collect to obtain the best content of phenolic compounds.