Homesickness is an ailment that affects a great number of college students, both in the United States and abroad. There is a lack of literature on homesickness and related psychological constructs for its occurrence, resulting in a substantial gap in researchers’ understanding of the phenomena. Advances in research on this topic may aid in both the development and improvement of treatments, helping students to be more successful academically and socially, which could result in lower college transfer and dropout rates. The purpose of the current study is to examine one specific protective factor, religiousness, and how it affects the relationship between homesickness and three negative outcomes (depression, substance use, risky sexual behaviors). Additionally important to the study is the use of multiple measures of religiousness. Religiousness research has suffered from a lack of theoretical backing, relying mostly upon singlemeasure items which may not always be the specific reason or way religiousness is involved. Thus, this research will advance the methodological approach to religiousness as well as provide a more precise and meaningful understanding of what specific aspect(s) of religiousness is involved in buffering homesickness’ negative results.