Each set of experiments was repeated for three times and only mean values of the results were discussed. Statistical analysis (ORIGIN software) of results for replicas showed a minimum standard deviation range of ± 3% for most of the experiments. (Fig. 1 depicts the variation in COD reduction of tannery saline wastewater salinity, 2% w/v) by salt tolerant bacterial isolates, mixed salt tolerant consortia and tannery sludge). A maximum degradation of 87.6% was observed for P.aeruginosa compared to tannery sludge (68.5%).Studies on effect of salinity already showed that P. aeruginosa was effective in adapting to low salt concentrations (>5% w/v) compared with the other strains reported. This finding was also reflected in the experimental resultsobtained from biodegradation of tannery saline wastewater and confirmed that P.aeruginosa was a suitable working strain for treatment of tannery effluent of low saline concentration.