A Framingham Heart Study report indicated that a weight increase of ≥2.25 kg over a period of 16 yr was associated with an up to 45% increased risk of developing the MetS [29], and it has been shown by Palaniappan et al. that each 11 cm increase in waist circumference (WC) is associated with an adjusted 80% increased risk of developing the syndrome within 5 years [30].