McBryde, Gardner, de Barros Lopes, and Jiranek (20 0 6)used
sequential batch fermentation for adaptive evolution of a wine
yeast strain. While the original strain gave rise to sluggish fer-mentations in a 20 0 g/L sugars synthetic must, the final mixed
culture obtained from adaptive evolution was able to complete
total sugar consumption. Cadière, Ortiz-Julien, Camarasa, and
Dequin (2011) using sequential batch cultivation on gluconate as
carbon source of a wine commercial strain obtained evolved strains
with increased flux towards the pentose phosphate pathway.