Liver homogenates of B6C3F1 mouse (Charles River, Germany; aged 8
10 weeks), Wistar rat
(Charles River, Germany; aged 12 weeks), New Zealand White rabbit (Broekman, The Netherlands;
aged 16 weeks), and beagle dog (Harlan, TheNetherlands; aged 12 13months)were prepared from fresh
livers. Liver homogenates of Yucatan micropig (Charles River, France; aged 9 10 months) and Macaca fascicularis monkey (Servier, UK; aged 26 27 months (males) and 18 24 months (females) were from frozen livers. Microsomes were prepared both from male and female animals.