Degenerative joint disease (DJD) or osteoarthritis in the equine is largely a result of
biomechanical stressors that result in inflammation within the joint, which with continual
exposure, leads to progressive degeneration. A myriad of therapies are available for
treatment of horses with DJD including nonsteroidal anti-inflammatory drugs, corticosteroids,
physiological modifiers, and biological therapies. C-phycocyanin, a protein-bound
pigment found in blue-green algae, has been shown to have anti-inflammatory and
antioxidant properties and is available as a diet supplement in people, dogs, and horses.
Forty-one horses with naturally occurring lameness as a result of DJD were selected for this
study. In a blinded study, horses were randomly assigned to either the commercial or
placebo product that was fed once daily for 12 months. At selected time points, lameness
evaluation was performed through objective gait analysis. Previous medical records for
management of lameness were reviewed for all enrolled horses. No statistically significant
differences existed within or between the two groups when gait was evaluated objectively
nor within individual horses between time points. Review of medical records found that
five treated horses had a decreased in frequency of intra-articular injection of corticosteroids.
Although this study did not find statistically significant improvement of lameness
with oral daily supplementation of C-phycocyanin in equine athletes, there appeared to be
a trend of improvement in lameness during the loading period and a decrease in frequency
of administration of intra-articular corticosteroids. Further investigations using a higher
dose seem warranted
Degenerative joint disease (DJD) or osteoarthritis in the equine is largely a result ofbiomechanical stressors that result in inflammation within the joint, which with continualexposure, leads to progressive degeneration. A myriad of therapies are available fortreatment of horses with DJD including nonsteroidal anti-inflammatory drugs, corticosteroids,physiological modifiers, and biological therapies. C-phycocyanin, a protein-boundpigment found in blue-green algae, has been shown to have anti-inflammatory andantioxidant properties and is available as a diet supplement in people, dogs, and horses.Forty-one horses with naturally occurring lameness as a result of DJD were selected for thisstudy. In a blinded study, horses were randomly assigned to either the commercial orplacebo product that was fed once daily for 12 months. At selected time points, lamenessevaluation was performed through objective gait analysis. Previous medical records formanagement of lameness were reviewed for all enrolled horses. No statistically significantdifferences existed within or between the two groups when gait was evaluated objectivelynor within individual horses between time points. Review of medical records found thatfive treated horses had a decreased in frequency of intra-articular injection of corticosteroids.Although this study did not find statistically significant improvement of lamenesswith oral daily supplementation of C-phycocyanin in equine athletes, there appeared to bea trend of improvement in lameness during the loading period and a decrease in frequencyof administration of intra-articular corticosteroids. Further investigations using a higherdose seem warranted
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