The diagnosis of fungal brain abscess id often unexpected and many cases are not discovered until autopsy.
In autopsy studies, Candida spp. have emerged as the most prevalent etiologic agents; neuropathological lesions include
micro abscesses, noncaseating granulomas, and diffuse glial nodules. Risk factors for invasive Candida infection include the use of corticosteroids, broad –spectrum antimicrobial therapy, and hyperalimentation.
Disease also seen in premature infants; in patients with malignancy, neutropenia, chronic granulomatous disease,
diabetesmellitus, or thermal injuries, and in patients with catheter in place