• The recommended insulin dose is a fixed rate intravenous insulin infusion (FRIII) given at 0.05 units per
kg per hour (e.g. 4 units/hr in an 80 kg man) is used. A fall of glucose at a rate of up to 5 mmol/L per hour is ideal and once the blood glucose has ceased to fall following initial fluid resuscitation,
reassessment of fluid intake and evaluation of renal function must be undertaken. Insulin may be
started at this point, or, if already in place, the infusion rate increased by 1 unit/hr. As with DKA, a
FRIII is preferred, though generally lower doses are required.
• The recommended insulin dose is a fixed rate intravenous insulin infusion (FRIII) given at 0.05 units perkg per hour (e.g. 4 units/hr in an 80 kg man) is used. A fall of glucose at a rate of up to 5 mmol/L per hour is ideal and once the blood glucose has ceased to fall following initial fluid resuscitation,reassessment of fluid intake and evaluation of renal function must be undertaken. Insulin may bestarted at this point, or, if already in place, the infusion rate increased by 1 unit/hr. As with DKA, aFRIII is preferred, though generally lower doses are required.
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