In the present decade, adolescents' mental problems are known as critical problems which have many destructive consequences. This study aimed to measure students'happiness and psychological well-being status in a sample of high school students in Tabriz,Iran. Numerous variables including general health status,happiness,self-efficacy,perceived stress,hopefulness and life satisfaction were measured by using self-reported written questionnaires.Significant relation observed between happiness and psychological well-being(r=0.48). Those students with good relationship and those who had reported to enjoy attending social events indicated better mental health status. No causal inferences were investigated due to the non-experimental nature of the study. The findings also revealed that students with higher happiness score have a better school performance. Integration of happiness promotion initiatives into the comprehensive school health programs is recommended to have pleasant environments for a healthy population of adolescents.