to reduce inflammation of the airway Antileukotrienes were administered to prevent leukotrienes, produced during exacerbation, from attaching to cell receptors in the lungs and arculation. It could also help in the inflammation. Lastly intravenous magnesium sulphate would relax the smooth muscle in the airway, thus breaking the spasm and inhibiting mast cell degranulation. In the ED, nurses ensured that Miss L was able to tolerate these medications and continued to monitor her vital signs closely GINA, 2012, Ornato, 2007)