Inflammation is a normal biological process in response to tissue
injury, microbial pathogen infection and chemical irritation.
This biological process also involves the innate and adaptive immune
systems. At a damaged site, inflammation is initiated by
migration of immune cells from blood vessels and release of mediators
to eliminate foreign pathogens and repairing injured tissues
(Medzhitov, 2008; Pan et al., 2009). The main function of inflammation
is beneficial for a host’s defence. In general, normal inflammation
is rapid and self-limiting, but aberrant resolution and
prolonged inflammation causes various chronic disorders (Calder
et al., 2009). Chronic inflammation can inflict more serious damage
to a host tissue than the infection. Studies showed that chronic
inflammation was linked to a wide range of progressive diseases,
including auto-immune disorders, neurological diseases, metabolic
disorder and cardiovascular diseases (Calder et al., 2009; Guha and