The name Physalis in Greek for ‘a bladder’ reference to the inflated calyx [4]. The genus Physalis is a member of the Nightshade family, Solanaceae. Physalis species are annual or perennial, erect or decumbent, sometimes rhizomatous, glabrous or pubescent, and with variously toothed or lobed leaves. Physalis is believed to have originated in Mexico, and there is only one species (P. alkekengi) whose origin is not of the New World, although many cultivated and weedy. This species have been introduced, both intentionally and inadvertently, to warm areas worldwide. Whitson has proposed separating P. alkekengi into a new genus, Alkekengi, and conserving the name Physalis for the rest of the species. This is based on recent molecular studies that separate Alkekengi, in addition to its distinctive red inflated calyx, lobed white flowers, and its unique Eurasian geographic distribution [5]. Historically, Physalis species have been taxonomically classified based on characters such as habit, hair type, and number of calyx angles [6]. The typical Physalis species is an herb with axillary yellow flowers that are solitary and bee pollinated [7].