However, the use of pesticides during production often leads to the presence of pesticide residues in fruit after harvest. Unfortunately, not all farmers follow legal prac-tices with pesticides during production. Therefore, pesti-cides should be controlled at optimum level due to their relative toxicity to the human health. Pesticide residue analysis is tremendously an important process in deter-mining the safety of using certain pesticides. A number of analytical methods are designed to determine multiple pesticide residues. In the past few years, new extraction procedures have been developed, such as solid-phase microextraction [4] and supercritical fluid extraction [5]. Pesticides are usually determined by gas chromatography (GC), GC-mass spectrometry, GC-ion trap mass spec-trometry [6] and GC–tandem mass spectrometry [7]. Besides GC–MS methods, there are other traditional quantification methods like high performance liquid chromatography (HPLC) [8], HPLC–mass spectrometry, low-pressure gas chromatography–mass spectrometry [9] and liquid chromatography–tandem mass spectrometry.