Antioxidant activity of different rice extract and the effect on the levels of antioxidant enzyme activity,
superoxide dismutase (SOD) and glutathione peroxidase (GPx), vitamin E, lipid peroxidation and liver
enzymes in hyperlipidaemia rabbits were investigated. Germinated brown rice (GBR) has the highest
antioxidant activity compared to white rice (WR) and brown rice (BR). All rice grains increased the activity
of SOD and GPx. However, vitamin E levels increased only in the groups that received the BR and GBR
diets. The reduction of lipid peroxidation levels and activity of hepatic enzymes (alanine transferase, ALT
and aspartate transaminase, AST) were only significantly observed in the GBR group. In conclusion, GBR
supplementation has the greatest impact on increasing antioxidant enzyme activity and vitamin E level
and on reducing lipid peroxidation in hypercholesterolaemia rabbit, thereby preventing the formation of
atherosclerotic plaques. Furthermore, GBR diet can also reduce the level of hepatic enzymes.