The aerobic endurance training intervention consists of moderate-intensity general dynamic endurance training on bicycle ergometers performed in accordance with the continuous training method. The participants thereby maintain a certain wattage and remain in a predominantly aerobic metabolic state. Heart rate is measured continuously. The blood lactate concentration measured during the baseline lactate threshold test allows us to determine the wattage at which the participant has to cycle to achieve a lactate concentration of approximately 2 mmol/l, which signifes an aerobic metabolic state. The participant should fnd the training “slightly strenuous” but should be able to talk without being short of breath. The training intensity is maintained until week 12, when we retest the lactate threshold and adjust the intensity if necessary