One of the reasons behind this significant increment is aeration factor. Previous studies reported that static culture had a difussion limitation problems. Microbial cellulose film that produced at the surface of medium will slowly restrict the diffusion of oxygen and nutrient. This will lead to inactivation or death of A.xylinum because of lack of oxygen and food. In RDR, the discs rotate and let A.xylinum in contact with the medium and air during fermentation. This automatically reduces or perhaps eliminates the diffussion limitation problems as in static culture fermentation.