However, despite the large number of studies on the fruits or leaves of mulberry, the effects of mulberry twigs on tyrosinase and quantitative antioxidant activity have rarely been examined. In view of the importance of decreasing both tyrosinase activity and oxidative reaction in foods to protect the nutritional components against oxidative damage, the aims of this study were to investigate the modulation capacity of mulberry twigs on tyrosinase activity and oxidative damage.