was found to be the only unique negative predictor of time to
remission and depression free days with SSRI use (McMakin et al.,
2012). Providing further generalizability across treatment modalities,
anhedonia was a predictor of non-response to repetitive
transcranial magnetic stimulation (rTMS) of the dorsomedial
prefrontal cortex in MDD (Downar et al., 2014).
Notably, there is a paucity of measures and tasks validated for
use in MDD that tap into the different facets of a “pleasure response”.
Traditionally, anhedonia has been defined as a “loss of
pleasure” (Ribot, 1986), a definition that emphasizes the consummatory/enjoyment
aspect of reward function. However, anhedonia
within the DSM-5 reflects a broader conceptualization
that includes interest as well as consummatory pleasure. Even
within the widely-used Hamilton Depression Rating Scale, a single
anhedonia item is used to measure a dimensional construct
was found to be the only unique negative predictor of time toremission and depression free days with SSRI use (McMakin et al.,2012). Providing further generalizability across treatment modalities,anhedonia was a predictor of non-response to repetitivetranscranial magnetic stimulation (rTMS) of the dorsomedialprefrontal cortex in MDD (Downar et al., 2014).Notably, there is a paucity of measures and tasks validated foruse in MDD that tap into the different facets of a “pleasure response”.Traditionally, anhedonia has been defined as a “loss ofpleasure” (Ribot, 1986), a definition that emphasizes the consummatory/enjoymentaspect of reward function. However, anhedoniawithin the DSM-5 reflects a broader conceptualizationthat includes interest as well as consummatory pleasure. Evenwithin the widely-used Hamilton Depression Rating Scale, a singleanhedonia item is used to measure a dimensional construct
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