The prevalence of atopic diseases such as allergic rhinitis
and asthma has increased in children and adults over the
past 3 decades [1]. House dust mites (HDMs) are common
allergens worldwide and Dermatophagoides pteronyssinus and
Dermatophagoides farinae are major allergens that coexist in
most geographical regions. Approximately 85% of asthmatics
are typically HDM-allergic [2]. Acaricides and environmental
control measures have been found to be of no effect in reducing
asthma or rhinitis symptoms [3,4]. While treatment with rescue
medications and corticosteroids can control allergic rhinitis
and asthma symptoms, with improvement of lung function in
asthmatics, it does not modify the natural course of disease