Patients’ initial perceptions and understanding of their AMI are important determinants of their recovery and motivation for lifestyle changes and secondary prevention.asserted that further research is needed to make comparisons between patients who received PPCI and who were thrombolysed to determine if the treatment experience affects compliance with secondary prevention.Presently there is no study that compares the treatment experience of patients treated for AMI by the different methods and its impact on their illness perception and compliance with secondary prevention. This study aimed to address that gap. This study was guided by the common sense model of self regulation of health and illness of Leventhal et al.11 (see Figure 1). Other theoretical frameworks were considered but Leventhal et al.’s model was chosen as it provides a dynamic framework for understanding the complexities of behaviours in response to events such as illness. This approach proposes that in response to an illness or health threat, people form their own common sense beliefs or illness perceptions about their illness and treatment. These illness perceptions influence the types of healthy behaviours and coping strategies that patients use for managing their illness and these may impact on disease outcomes.