Hypertension is the most common condition seen in primary care and leads to myocardial
infarction, stroke, renal failure, and death if not detected early and treated appropriately.
Patients want to be assured that blood pressure (BP) treatment will reduce their disease
burden, while clinicians want guidance on hypertension management using the best scientific
evidence. This report takes a rigorous, evidence-based approach to recommend treatment
thresholds, goals, and medications in the management of hypertension in adults. Evidence
was drawn from randomized controlled trials, which represent the gold standard for
determining efficacy and effectiveness. Evidence quality and recommendations were graded
based on their effect on important outcomes.