Comparison of secondary outcome between the ECF and DRI group did not show significant differences in severe intraventicular hemorrhage (>grade 2) (3/24 (12.5%) vs. 3/49 (6.1%)), cystic periventricular leucomalacia (0/24 (0%) vs. 2/24 (4%)) and patent ductus arteriosus requiring medical or surgical closure (5/25 (20%) vs. 15/50 (30%)).