However, insulin production does not always depend
on blood glucose levels; insulin is stored in cells prior to
its release. Insulin deficiency plays a central role in all
forms of diabetes because it is the major hormone that
enables cells (primarily muscle and fat cells) to uptake
glucose from the bloodstream. Insulin makes it possible
for most body tissues to remove glucose from the blood
for use as fuel, for conversion to other needed
molecules, or for storage. Furthermore, insulin is also
the major regulatory signal for glycogenesis in the
hepatocytes and myocytes