Universal Fermenter from 500 ml up to 17.5 l with scale-up possibility from Laboratory up to industrial scale. Our fermenters make possible a shear stress-free cultivation of adherent cells, in serum or protein free media and high cell-density in long-term-cultivation. 100 ml fixed-bed bioreactor for cell cultivation in incubator. fixed-bed bio reactors consist of fixed-bed vessels, working volume 5 ml up to 6,5 litre and outer vessel total volume 100 ml up to 17,5 litre. The macro-porous materials which be needed for the cultivation are in the fixed-bed vessel.