Wedidnotfindaneffectof3-moaerobicexerciseintervention
alone on serum AGE levels. This differs from three previous re-
ported studies looking at the effect of exercise on AGE levels in
general.ThefirststudiedtheeffectoftaichiinahealthyMalaysian
population matched with sedentary volunteers >45 y [16]. The
participants were randomized either to practice tai chi twice per
week or to a control group. Plasma malondialdehyde and AGE
concentrations decreased significantly after 12 mo only in the tai
chi group. The second study recruited 17 healthy women (aged
30–60 y) who participated in a lifestyle modification protocol
aimedatincreasingphysicalactivity for3motomeasurechanges
in AGEs [24]. Blood levels of CML decreased in the treatment
group compared with controls and changes in CML levels corre-
latedwiththeintensityofexercise.Finally,thethirdgroupstudied
levels of MG in red blood cells during exercise in eight untrained
and five trained men [32]. Each man performed runs of short and
long duration. MG content of red blood cells decreased markedly
after running, especially in the untrained men. After short runs,
the MG concentration had dropped to 13% in the untrained men
and30%inthetrainedmen,andafterlongrunstheconcentration
fell to 41% in the untrained and 60% in the trained men. Our
different results likely reflect the different populations studied
and, more importantly, the type and intensity of exercise inter-
vention. We should note that our study followed the American
CollegeofSportsMedicineGuidelinessupportingaerobicexercise
performed 3 to 5 d/wk for 20 to 60 continuous minutes at an in-
tensity of 55% to 90% of HR max
Wedidnotfindaneffectof3-moaerobicexerciseinterventionalone on serum AGE levels. This differs from three previous re-ported studies looking at the effect of exercise on AGE levels ingeneral.ThefirststudiedtheeffectoftaichiinahealthyMalaysianpopulation matched with sedentary volunteers >45 y [16]. Theparticipants were randomized either to practice tai chi twice perweek or to a control group. Plasma malondialdehyde and AGEconcentrations decreased significantly after 12 mo only in the taichi group. The second study recruited 17 healthy women (aged30–60 y) who participated in a lifestyle modification protocolaimedatincreasingphysicalactivity for3motomeasurechangesin AGEs [24]. Blood levels of CML decreased in the treatmentgroup compared with controls and changes in CML levels corre-latedwiththeintensityofexercise.Finally,thethirdgroupstudiedlevels of MG in red blood cells during exercise in eight untrainedand five trained men [32]. Each man performed runs of short andlong duration. MG content of red blood cells decreased markedlyafter running, especially in the untrained men. After short runs,the MG concentration had dropped to 13% in the untrained menand30%inthetrainedmen,andafterlongrunstheconcentrationfell to 41% in the untrained and 60% in the trained men. Ourdifferent results likely reflect the different populations studiedand, more importantly, the type and intensity of exercise inter-vention เราควรทราบว่า การศึกษาของเราตามที่อเมริกันCollegeofSportsMedicineGuidelinessupportingaerobicexerciseทำ 3-5 d/wk 20-60 นาทีต่อเนื่องที่มีในtensity ของ 55% ถึง 90% ของ HR max
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