Primary aldosteronism (PA), one of

Primary aldosteronism (PA), one of the most common
causes of treatment-resistant hypertension (TRH), has
been identified in up to 20% of patients with TRH seen in tertiary hypertension centers. TRH patients with medication nonadherence (ie, pseudo-TRH) are presumed to have a lower prevalence of PA than those with true TRH. Consequently, the 2008 American Heart Association (AHA) position statement recommends investigation for PA, or other causes of secondary hypertension, in patients with apparent TRH after nonadherence to medications is excluded. In the same guideline, further testing for secondary hypertension in nonadherent patients was not recommended.