Solvents
were purified according to the standard procedures.
All the other reagents were provided by Enamine LTD.C NMR spectra were recorded on Bruker Avance 500 spectrometer (at 499.9 MHz, 470.3 MHz and 124.9 MHz). Chemical shifts are reported in ppm downfield from TMS (1H,13C) or CFCl3(19F) as
internal standards. MS analyses were done on an LCMS instrument with chemical ionization (CI) or GCMS instrument with electron impact ionization (EI).