Erythromycin base (not erythromycin estolate,which is associatedwith cholestatic hepatitis in pregnancy) or clindamycin
(Cleocin; both FDA pregnancy category B)
can be used in the type 1 hypersensitivity
penicillin–allergic patient. For severe cellulitis, the patient should be hospitalized and
treated with intravenous cephalosporins or clindamycin. To manage dental pain, acetaminophen (FDA pregnancy category B),ibuprofen (Motrin; FDA pregnancy category B in the first and second trimesters, category
D in the third trimester), and limited use of oxycodone (Roxicodone; FDA pregnancy
category B in the first and second trimesters, category D in the third trimester) are appropriate depending on the gestational stage.