Preparation of andrographolide-enriched extract of A. paniculata leaves: A. paniculata (Burm. f.) Nees was collected in August 2012 from the area around Yogyakarta, Indonesia. The leaves were shade dried, powdered and stored in an airtight container for further use. The plant was authenticated by a botanist at Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Gadjah Mada, Indonesia and the voucher specimen was deposited in herbarium of the department.