Chitosan was used to modify cellulose/SPI composites by e blending or surface coating, with the aim of enhancing the physical properties, cytocompatibility and hemocompatibility of the resultant composites.(2011), Chitosan could interact with tant composites (Wang et both cellulose and SPI and enhance their properties. Chitosan coating could alter the surface morphology of the original cellulose-Soy Protein lsolate Membrane (CsM) by covering the pores on the CSM by forming a very thin layer during the coating process. These changes were found to affect the microstructure, physical properties and biological properties of the resulting membranes Water sorption isotherms of soy protein isolate/carboxymethyl chitosan (SPI/CMCH) blended films was studied by R tanapun The Guggenheim-os Bru (2012) iriyatem nauer-Emmett-Teller (BET) and Anderson-de Boer (GAB) sorp tion model predictions were tested against the experimental data The isotherms showed that the equilibrium moisture content (EMC) of the films increased with increasing CMCH content and the EMC value sharply increased above water activity (aw) 0.55. The BET model was found to be the best-fit model for SPl CMCH blended films at 25 t 1 C. Hemocompatib of CH/SPI composite membranes was improved by heparinization by Wang. Shi, et 2012), It was observed that compared with chitosan/soy protein (Chs) mem branes, heparinized chitosan/soy protein (HChS) membranes showed lower platelet adhesion, longer plasma recalcification (PRT), higher blood anticoagulant index (BCI), significant thromboresistivity and lower hemolysis rate due to the heparinization recent years, great interest has been given to the stud tein-polysaccharide mixtures both in the indu s, The manipulation of the protein polysaccharide