1.Introduction
Congenital syphilis is a severe, disabling infection often with
grave consequences seen in infants. Syphilis continues to
affect pregnant population, in spite of numerous control
measures in place established for its prevention. Worldwide,
World Health Organization (WHO) estimates that two
million pregnant women get infected with syphilis, every
year[1].Withoutadequatetreatmentmanyofthemtransmit
this infection to their offspring, thus increasing the number
of reported cases of stillborn, preterm, low birth weight, or
congenital infection.
Congenital syphilis results from transplacental transmis-
sion of spirochetes. Approximately 66% of infected infants
from congenital syphilis are asymptomatic at the time of
birth and are identified only by routine prenatal screening.
Untreated syphilis during pregnancy has a transmission rate
nearing 100%. Fetal or perinatal death occurs in 40% of
affected infants [2]. Clinical signs appear in approximately
two-thirds of affected infants from 3rd to 8th week of life
and in most cases by three months of age [3]. Primary
skeletal involvement is rare [4]. We are reporting one such
case of symptomatic congenital syphilis that presented with
skeletal manifestations soon after birth, a rare finding in
literature [5].
1. 1.Introduction
บทนำซิฟิลิสCongenital syphilis is a severe, disabling infection often with
แต่กำเนิดเป็นรุนแรงมักจะปิดการใช้งานการติดเชื้อผลกระทบร้ายแรงที่เห็นในเด็กทารก ซิฟิลิสยังคงส่งผลกระทบต่อประชากรตั้งครรภ์ทั้งๆที่มีการควบคุมหลายมาตรการในสถานที่จัดตั้งขึ้นสำหรับการป้องกันของ grave consequences seen in infants. Syphilis continues to
affect pregnant population, in spite of numerous control
measures in place established for its prevention. Worldwide,
World Health Organization (WHO) estimates that two
million pregnant women get infected with syphilis, every
year[1].Withoutadequatetreatmentmanyofthemtransmit
this infection to their offspring, thus increasing the number
of reported cases of stillborn, preterm, low birth weight, or
congenital infection.
Congenital syphilis results from transplacental transmis-
sion of spirochetes. Approximately 66% of infected infants
from congenital syphilis are asymptomatic at the time of
birth and are identified only by routine prenatal screening.
Untreated syphilis during pregnancy has a transmission rate
nearing 100%. Fetal or perinatal death occurs in 40% of
affected infants [2]. Clinical signs appear in approximately
two-thirds of affected infants from 3rd to 8th week of life
and in most cases by three months of age [3]. Primary
skeletal involvement is rare [4]. We are reporting one such
case of symptomatic congenital syphilis that presented with
skeletal manifestations soon after birth, a rare finding in
literature [5].
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