As PHAs are insoluble in water, the polymers are accumulated
in intracellular granules inside the cells. It is
advantageous for bacteria to store excess nutrients inside
their cells, especially as their general physiological fitness
is not affected. By polymerizing soluble intermediates into
insoluble molecules, the cell does not undergo alterations
of its osmotic state. Thus, leakage of these valuable compounds
out of the cell is prevented and the nutrient
stores will remain securely available at a low maintenance
cost