All the date palm extracts tested including leaf, fruit, seeds and bark showed antibacterial activity (Table 1). Results obtained in the present study show that plants extract possesses potential antibacterial activity against the tested organisms; however, methanol and acetone extracts was found to be more effective antimicrobial agents than the aqueous extracts (Table 1). The fruit and leaves extract showed better antibacterial activity than seed and bark extracts. In fact, high antibacterial activity against all test organisms was observed with acetone fruit extract against S. aureus (18.2 ± 0.55 mm). Leaf extract showed highest activity against E. coli in response to methanol extract (13.5 ± 0.33 mm). Seeds and bark extracts showed almost similar antibacterial activity