Cells and cell cultures. A549 andH1437 were established from a human
lung adenocarcinoma and a human non-small cell lung carcinoma,
respectively. These cell-lines were routinely cultured in RPMI-1640
medium. Human embryonic kidney 293 cells (HEK-293) were cultured
in DMEM medium and were used for generating the replication deficient
adenovirus.