The K and R values in Table 3 were calculated following the procedures described by Ling et al. [11]. The R value showed that adding amount of perilla powder had the most significant effect on the organoleptic properties of perilla chewable, and the order of importance that influenced the organoleptic properties of perilla chewable tablet was found to be as follows: adding amount of perilla powder (factor A)> adding amount of adhesive mixtures (factor B)> adding amount of perilla extract powder (factor C). In addition, the K value of factor A, factor B and factor C had the highest value at level 2, level 3 and level 1, respectively. It indicated that the optimal formula compositions were 8% of perilla powder, 40% of adhesive mixtures and 2.5% perilla extract powder. Thus, combined this result with other some preliminary experiments (data not shown), we concluded the optimal formula of perilla chewable tablet and shown in Table 4.