Based on our observations, it is possible that the somatic, social and psychological QOL of cancer
patients may be improved by combined treatment modalities. Patterns of change in the QOL during
treatment can be influenced by several factors such as age and gender. Both pretreatment emotional
status and improvement of QOL during the course of treatment may positively influence the objective
treatment outcome. HT-based therapy can be used without negative impact on the QOL for a long
treatment period.