This study highlighted Patatin as a potential replacement of conventional fining agents used to improve the settling of white musts because of: (i) good flocculating activity (higher than 85% after 3 h of contact at the dose of 30 g/hL), (ii) a browning inhibition activity higher than potassium caseinate and (iii) the feature of being less allergic for human. Patatin is also economically attractive because its production allows to exploit waste water from potato processing that is a waste by-product. Therefore, more detailed researches are needed in order to evaluate the effect of important parameters such as pH and temperature on flocculating activity of P, as well as the capacity to retain important components of musts as aroma precursors or pest residues during settling.