of the procedure for total metal determination has been assessed by analyzing different certified reference materials (DORM-2, BCR 279 and
NIES-09); whereas, trueness for the in vitro bioavailability method has been established after performing
a mass balance study. Low (2.6–10.8%) and moderate (21.5–41.3%) dialyzability percentages have been
found in seafood samples. However, high dialyzability percentages (30.0–74.7%) have been found in edible seaweeds. Linear and quadratic models have shown that the bioavailability of some metals exhibited
good positive correlation with the carbohydrate content and also with the dietary fibre level. Protein content showed good negative correlation with the bioavailability of certain metals, whereas, moderate negative correlation was found with fat content.