Conclusions
Immunotherapy with its immune modulator effects is very important part in the treatment of children with asthma and allergic rhinitis. Current data have shown clinical efficacy of SLIT in children with AR, but the data on clinical efficacy of SLIT in asthma are controversial. Symptoms and rescue medicaments intake are a reasonable outcome measure, but objective parameters like FEV1 and PEF should be included as co primary endpoints.