Despite extensive investigations, no consensus on the
source, size and other biochemical or physicochemical
properties of beta-1,3-glucan has been achieved. In addition,
numerous concentrations and routes of administration
have been tested – including oral, intraperitoneal,
subcutaneous and intravenous applications. Besides, there
are probably more than a hundred of different samples on
the U.S. market alone, which leads to a confusion about
the quality, biological effects and overall efficiency of glucan.
Therefore, we decided to compare the basic biological
and immunological activities of a group of glucans.